Measuring and using free drug concentrations: has there been ‘real’ progress?
نویسندگان
چکیده
منابع مشابه
Never Has There Been a Shade1
“O this date [in 1618] Abu’l Hasan the artist, who had been awarded the title Nadir al-Zaman [Wonder of the Age], presented a painting he had made .... Since it was worthy of praise, he was shown limitless favor. Without exaggeration, his work is perfect, and his depiction is a masterpiece of the age.” These were the words of Emperor Jahangir of the Mughal Dynasty of India. “Abu’l Hasan’s fathe...
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Pregnancy in women with pulmonary arterial hypertension (PAH) is considered to be associated with prohibitive maternal mortality. During the past decade, new advanced therapies for PAH have emerged and progress in high-risk pregnancy management has been made. We examined whether these changes have improved outcomes in parturients with PAH. A systematic review of all cases of parturients with id...
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BACKGROUND Compliance is a key element in the success of therapy, both in practice and research. A study from 1974 demonstrated that compliance in clinical trials was only determined in 19% of studies requiring it. OBJECTIVES The objective was to determine if there has been an improvement in compliance assessment in clinical trials. METHODS All drug studies published in the British Medical ...
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Amid the renewed concern in the last several years about the potential for life science research to facilitate the spread of disease, a central plank of the policy response has been to enact processes for assessing the risks and benefits of "research of concern." The recent controversy regarding a proposed redaction of work on the modification of a H5N1 avian influenza virus is perhaps the most...
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ژورنال
عنوان ژورنال: Bioanalysis
سال: 2017
ISSN: 1757-6180,1757-6199
DOI: 10.4155/bio-2017-0053